I'm a Chrome user on Mac and Windows, so of course I wanted to try it on the iPad, and I liked it immediately.
But I don't think I can switch from Safari. One reason is the toolbar bookmarks don't work the same way they work in the desktop versions of Chrome and in Safari on the iPad. It's three steps to click on a bookmark, and in Safari it's just one. That's a huge difference, where there are a set of pages I visit regularly.
Also Twitter for some reason gives me a mobile interface on Chrome and on Safari gives me the normal interface. Why sites keep treating iPads differently from desktops is a mystery to me. It's got a full-size screen. Don't be so fancy, "different" is not better.
However, I'd like to be able to switch to Chrome to have everything all synched up across all my platforms. Maybe they can address the bookmarks question in an update, or maybe I'm missing something??